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The world's only research centre on mycetoma, a neglected tropical disease common among farmers, has been destroyed in Sudan's two-year war, its director and another expert say.

The World Health Organization chief said Tuesday that operations and jobs would be slashed as US funding cuts had left the UN agency with a budget hole of several hundred million dollars.

The United States slashing foreign aid risks piling pressure on already acute humanitarian crises across the globe, a World Health Organization official said Sunday, also warning against withdrawing from the UN agency.

Years of negotiations culminated early Wednesday with countries agreeing the text of a landmark accord on how to tackle future pandemics, aimed at avoiding the mistakes made during the Covid-19 crisis.

After more than three years of thorny negotiations, World Health Organization member states finalised early Wednesday a major agreement on pandemic prevention, preparedness and response.

More than 10 percent of the Afghan population could be deprived of healthcare by the end of the year due to the termination of US aid, the World Health Organization warned Tuesday.

World Health Organization members on Saturday reached agreement over how to tackle future pandemics after three years of discussions, the co-chair of the negotiating body told AFP.

Negotiations toward a global agreement on tackling future pandemics came down to the wire Friday, with observers voicing hope that a  consensus could be found to seal a landmark deal.

The World Health Organization is facing a gaping deficit this year and through 2027 following the US decision to withdraw, even after dramatically slashing its budget, a media report indicated on Wednesday.

The World Health Organization has proposed slashing a fifth of its budget following the US decision to withdraw, and must now reduce its reach and workforce, its chief said in an internal email seen by AFP on Saturday.